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Experience with automation in Next Generation Sequencing applications

  • 1.  Experience with automation in Next Generation Sequencing applications

    Posted 6 hours ago

    Dear all, 

    I'm Jens, a lab technician working for the Genomics Core facility, part of the Center for Human Genetics in the University Hospitals Leuven, Belgium.
    Our team makes NGS sequencing more accessible for caretakers, researchers and companies and we offer both long read (PacBio and ONT) and short read (Illumina) sequencing.

    We are currently increasing our efforts in automating the manual wetlab procedures, such as library prep and targeted enrichment. We are near completion of the development and validation of the Twist Library prep EF2.0 followed by the Twist Fast Hybridization targeted enrichment (both protocols attached) on our Hamilton NGS Star robots, but we have encountered a few difficulties.

    Are there any users who want to share their knowledge and have experience with

    • Hamilton NGS Star liquid handlers,
    • Twist Fast Hybridization
    • or ideally with the combination

    Any feedback would be highly appreciated! 

    Best regards

    Jens

    P.S. I will attend SLAS Europe 2026 (first time visiting a SLAS conference)



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    Jens Van Bouwel
    Lab Technician
    UZ Leuven
    Leuven
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